Diabetes and obesity are hidden cancer causes: Study -

Diabetes and obesity are hidden cancer causes: Study

Credit: straitstimes.com

  • Dec 07 2017 21:25About: 4 days ago
  • 10 views

Does a widening waistline put you at risk for cancer? Apparently so. Based on a new study, nearly 6 per cent of cancers are attributable at least in part to obesity and diabetes.

Researchers compared incidence data for 12 cancers in 175 countries in 2012 with body mass index and diabetes prevalence figures from 2002, on the assumption that it takes at least 10 years for cancer to develop. They found that in 2012, diabetes and a body-mass index (BMI) above 25 were independent risk factors for 792,600 new cases of cancer, about 5.6 per cent of the more than 14 million cases reported to a worldwide cancer registry.

Among the cancers associated with diabetes and high BMI were tumours of the colon, gall bladder, liver and pancreas. Obesity and diabetes were not the only causes of these cancers, but the conditions played a role.

"We know a lot about what causes obesity and diabetes, but what it is about being obese or diabetic that causes cancer is less clear," said lead author Jonathan Pearson-Stuttard, a clinical fellow at Imperial College London. "It may be that exposure to high insulin levels or insulin resistance may also be a cause of cancer."

The study, in The Lancet Diabetes and Endocrinology, found considerable differences in the proportions of cancer cases attributable to BMI on the one hand and to diabetes on the other.

For example, high BMI was associated with about twice as many cases of colorectal cancer as diabetes, and nearly three times as many cases of breast and endometrial cancers. Diabetes was not associated with kidney cancer at all, but high BMI was linked to about one-fifth of kidney cancer cases.

Among the cancers associated with diabetes and high BMI were tumours of the colon, gall bladder, liver and pancreas.

High BMI and diabetes combined accounted for 38.4 per cent of endometrial cancers but only 8.9 per cent of breast cancers. In men, the two conditions combined made up 23.3 per cent of liver cancers but just 8.6 per cent of colorectal cancers.

There were variations by region as well. About 16 per cent of cancer cases were attributable to high BMI in high-income Western countries. But only about 5 per cent of cancer cases in the high-income Asia-Pacific region were linked to BMI.

Diabetes and obesity are increasing worldwide, and the researchers project that cancers, particularly those of the gall bladder, liver and endometrium, will rise as well.

Unless diabetes and obesity are much better controlled, the growth in cancers will be significant.

"By 2035, because of increases in obesity and diabetes, there could be a 20 per cent increase in men's cancer and a 30 per cent increase for women," Dr Pearson-Stuttard said.

NYTIMES



Follow Us on Twitter

December 2017 5:00 AMDoes widening waistline risk cancer? Apparently Based study nearly cent cancers attributable least part obesity diabetes.

Related stories with Diabetes and obesity are hidden cancer causes: Study

The prettiest Christmas trees are underwater -World News
The prettiest Christmas trees are underwater 4 days ago
December 08, 2017 5:00 AMYour Christmas tree is nice - really, it is. It's just the right height and shape, so green, and it smells so good. You definitely picked the best one in all of the land.
Art and Museums in NYC This Week -World News
Art and Museums in NYC This Week 4 days ago
Our guide to new art shows, and some that will be closing soon.
Ask a Showrunner: ‘Runaways’ Showrunners Josh Schwartz and Stephanie Savage on Adapting a Beloved Comic -World News
Ask a Showrunner: ‘Runaways’ Showrunners Josh Schwartz and Stephanie Savage on Adapting a Beloved Comic 4 days ago
The writer-producer team behind “The O.C.” and “Gossip Girl” talk about their Hulu series.
Pop, Rock and Jazz in NYC This Week -World News
Pop, Rock and Jazz in NYC This Week 4 days ago
Our guide to pop and rock shows and the best of live jazz.
Santa's here from Lapland to meet needy kids -World News
Santa's here from Lapland to meet needy kids 4 days ago
Thirty-three underprivileged children enjoyed an early yuletide treat at Gardens by the Bay yesterday morning. They met a special Santa who had flown in from Lapland, Finland - billed as the unofficial home of Santa Claus. The children from Hope Ce
Razer’s next piece of gaming hardware is a wireless mesh router for gamers -World News
Razer’s next piece of gaming hardware is a wireless mesh router for gamers 4 days ago
Razer has partnered with Ignition Labs to release a new version of is Portal router tuned especially for gamers.
PS5: what will the Sony PlayStation 5 be like and when will we see it? -World News
PS5: what will the Sony PlayStation 5 be like and when will we see it? 4 days ago
PS5: All our hopes, desires and dreams for Sony's fifth major home video game console.
Far Cry 5 trailers, release date, news and features
 -World News
Far Cry 5 trailers, release date, news and features 4 days ago
Need your fix of open-world anarchy? Far Cry 5 is going to have it in spades.
Group Claims Mormon Church Members Baptized President Trump’s Dead Parents and Grandparents -World News
Group Claims Mormon Church Members Baptized President Trump’s Dead Parents and Grandparents 4 days ago
SALT LAKE CITY – A whistleblower organization has released documents indicating Mormon church members performed baptisms and other temple ordinances on behalf of President Trump’s dead parents and grandparents. The records are the latest from Morm
EastEnders spoilers: Max Branning FINISHED as new explosive secrets are revealed -World News
EastEnders spoilers: Max Branning FINISHED as new explosive secrets are revealed 4 days ago
MAX BRANNING finally exposed the truth surrounding his devious plans in tonight's EastEnders.
Here's the difference between 'turbo lag' and 'boost threshold' -World News
Here's the difference between 'turbo lag' and 'boost threshold' 4 days ago
If you’ve ever driven a car with a turbocharger like a Subaru WRX STI, old Mitsubishi Eclipse or any early examples of turbocharged cars, you’ll sometimes feel a sudden rush of power ...
Merkel demands better access to Libyan refugee camps -World News
Merkel demands better access to Libyan refugee camps 4 days ago
German Chancellor Angela Merkel has met with the head of Libya's internationally recognized government, Fayez al-Sarraj. She said "there is still a lot to do" to improve migrant conditions in the country.